Question: [The Mishnah said that] we prepare another Kohen in place of him, if a Pesul will occur to him. Do we separate [the replacement] together with [the Kohen Gadol]?

Answer (R. Chagai from there (Bavel)): We do not separate him with him, lest [the Kohen Gadol] kill him [amidst enmity].

"Oso'' - we anoint one [Kohen Gadol], and we do not anoint two.

(R. Yochanan): This is due to enmity.

If a Kohen Gadol passed (was unable to serve), and this served [in place of him], the first [when he can serve again] has all Kedushas Kohen [Gadol], and the second is not Kosher to serve, not as a Kohen Gadol (wearing the eight garments) and not as a Kohen Hedyot.

(R. Yochanan): If [the latter] transgressed and served [as a Kohen Gadol], his Avodah is Kosher.

Question: [If a Kohen Gadol cannot serve on Yom Kipur, and the substitute serves in place of him,] of whom is the Avodah (Par Yom Kipur)?

Answer: We learn from the following. A case occurred with Ben Ilem of Tziporin in which Tum'ah (not a seminal emission) occurred to the Kohen Gadol on Yom Kipur, and Ben Ilem served in place of him as Kohen Gadol;

When he left [the Mikdash], he said "my master, the king! The bull and ram of Yom Kipur - from whose [money] were they offered - from mine, or from the Kohen Gadol's?

The king understood what he asked (they are from him only if he will continue to serve). He told him "Ben Ilem - it is not enough for you that you served once in front of the One who said and the world was created?!'' Ben Ilem knew that he was deposed from Kehunah Gedolah. (Tosfos 12a DH Kohen - a king can depose the Kohen Gadol.)

A case occurred in which Shimon ben Kimchis left to speak with the [Nochri] king on Erev Yom Kipur, and spit from the king's mouth splashed on his garment and was Metamei him. His brother Yehudah entered to serve in place of him. Their mother saw two of her sons as Kohanim Gedolim in one day.

Kimchis had seven sons, and all of them served in Kehunah Gedolah. Chachamim sent to her and said "what are you good deeds [through which you merited this]?''

She told them "[punishments] should come upon me if the ceiling beams of my house saw the hairs of my head (it was never uncovered) or the bottom edge of my cloak (she never lifted it, and she changed clothes under a sheet).''

They say, all flour is flour (there are many Tzenu'os), but the flour of Kimchis was Soles (fine flour. Only she merited seven sons who were Kohen Gadol.) They applied to her "Kol Kevodah Bas Melech Penimah Mishbetzos Zahav Levushah.''