What is the meaning of the description, "Pere Adam"?
Rashi: The angel is informing Hagar that Yishmael will love hunting in the desert, as the Pasuk writes later (Bereishis 21:20) "And he dwelt in Midbar Paran 1 ...." According to Rashi's translation of "Pera'im" (Iyov 24:5), it means that he ran wild in the desert to rob and kill innocent wayfarers.
Ramban: "Pere" Adam" is like "Ish Pere" - a wild man who is trained to work in the desert
What did the angel mean by, "his hand against everyone and everyone's hand against him"?
Rashi: He meant that Yishmael will be a robber and everyone will hate him for it and fight with him.
Ramban #1: It refers to the wars that his children will fight with all the other nations and that the other nations will fight with them.
Ramban #2 (citing Ibn Ezra): Initially, Yishma'el's children will defeat the other nations, but ultimately, the other nations will defeat them.
Targum Yonasan: His hand will be outstretched to fight his enemies and their hand will be outstretched to fight him.
What does "Al P'nei Kol Echav Yishkon" mean?