(Mishnah): Ma'aser Sheni - one may not sell it, give it as collateral, exchange it or use it as a weight. In Yerushalayim, one should not say to his friend, "Take this wine and give me oil'' and the same is true for all other fruits, but a person may give his friend a free gift of Ma'aser Sheni.

Maaser Behemah - one may not sell it alive and unblemished; nor blemished, whether alive or slaughtered. And one may not use it to betroth a woman.

A Bechor (firstborn animal) - one may sell it unblemished if alive and blemished whether alive or slaughtered and one may use it to betroth a woman.

One may not redeem the Kedushah of Ma'aser Sheni onto a token, onto a coin that is not spendable or onto money that is not in his possession.

(Gemara): 'Ma'aser Sheni - one may not sell it etc.' One may not sell it because the pasuk ascribes it Kedusha (as it states in reference to Ma'aser Sheni (Vayikra 27:30), "Any tithe of the Land, whether it be from the seed of the land or the fruit of the tree it is Hash-m's; it is Holy to Hash-m.'')

One may not use it as collateral as the pasuk refers to it as a blessing (from Hash-m, as the pasuk states (Devarim 14:24), "for Hash-m, you G-d, will bless you''.)

How may one not sell it? He shouldn't say to his friend, "Take this 100 Zuz of Ma'aser Sheni and give me 50 Zuz of Chulin''.

Who is the Tana that says that one may not sell it? It's R. Meir; but according to R. Yehuda, it should be permitted to sell it based on a Kal Vechomer...If Terumah, which is prohibited to non-Kohanim is permitted to sell; Ma'aser Sheni, which is permitted to Kohanim will certainly be permitted to sell.

Rebuttal: No, if you say it for Terumah, that doesn't need to be eaten within the walls (of Yerushalayim); would you say it for Ma'aser Sheni that does need to be eaten there?!

Reinstatement: Bikurim prove it, as they must be brought within the walls but they may be sold.

Rebuttal: Bikurim are different as when they are sold, their Kedusha is not transferred onto the money.

Reinstatement: Sheviis proves it, as the Kedusha is transferred but it may be sold (under certain conditions).

Rebuttal (R. Yudan): Sheviis is different - the sale of Sheviis is actually its removal of Kedusha. (The Kal Vechomer about R. Yehuda's opinion is ultimately refuted.)