Rashi and Targum Yonasan (in Pasuk 15): Someone who withholds the Matnos Kehunah from the Kohen, will ultimately need to bring him his wife as a Sotah. ¹

Sotah, 24a: To include an Arusah and a Shomeres Yavam ¹ in the Din of Sotah. ²

Sotah, 26a: To include the wife of a Ger and of an Eved Cana'ani ³ in the Din of Sotah.

Rashi: Because the woman sinned against two 'Men' - her husband and Hashem, the "Ish Milchamah". ¹

Sotah, 27a: To include the wife of a Cheresh, a Shoteh, of a man who is deeply depressed, a man who traveled overseas, or who has been incarcerated - all of whom Beis-Din warn the woman who will subsequently forfeit her Kesubah. ²

Oznayim la'Torah #1: On the same words - "Ish Ish ... " #1 - in Beha'aloscha, 9:10, in connection with someone who is Tamei on Erev Pesach, Chazal Darshen 'Ish Nidcheh le'Pesach Sheini, ve'Ein Tzibur Nidcheh ... ' (an individual is pushed away to bring the Pesach Sheini, but not a Tzibur). The same words here therefore hint at what Chazal say that it is only as long as there were a few individuals who commited adultery that the miracle of Mei Sotah applied, but when the number of adulterers increased, the Mei Sotah ceased to function. ³

Oznayim la'Torah #2 DH 'Ish Ish ... ' #2: It is a hint that if a man commits adultery with his freind's wife, another man will commit adultery with his wife.

Rashi #1 (citing the Tanchuma): "Ki Sisteh Ishto" is like "Sishteh" (with a 'Shin'), ¹ because people do not commit adultery unless a spirit of Sh'tus (folly) enters into them. ²

Rashi #2, Rashbam and Seforno: It means that the woman strays ³ from the path of Tzeniyus, and her husband suspects her.

Sifri: "Ishto" implies a woman who is fit to be his wife - to preclude an Almanah who is married to a Kohen Gadol and a Chalutzah who is married to a Kohen Hedyot - and other similar Pesulim. ⁴

Rashi: Refer to Vayikra, 5:15:1:1. ¹

Ramban, Targum Onkelos and Targum Yonasan: Refer to Vayikra, 5:15:1:2.

Seforno: 'She desecrated ?the holiness of Hashem that He loves? ² with regard to the sanctity of marriage, by hugging and kissing - and performing similar acts with another man'. ³

Moshav Zekeinim (in Pasuk 9, citing R. Yehudah ha'Chasid): When a man goes to the Beis-Hamikdash on Yom-Tov, sometimes lewd men remain, and he may suspect that she sinned without witnesses; or he might neglect the Mitzvah of Aliyah le'Regel, in order to stay to guard his wife.

Kli Yakar: Rashi wrote that if one does not give Ma'asros, his field will produce one tenth of what it used to. Consequently, his wife, suspecting that he became poor due to promiscuity, ¹ will take her cue from him and commit adultery. Kol Eliyahu: She will make herself Hefker without fear - since she thinks that he is not innocent, and the Mei Sotah will therefore not affect her. And that is why he will need to bring her to drink!

Torah Temimah: In keeping with the Gemara in Sotah, 2a 'A man receives the wife he deserves - based on his deeds. ²

Oznayim la'Torah: Like Korach and King Uziyah He 'quarreled' with the Kehunah, which the Torah calls 'Me'ilah', ³ therefore his wife was Mo'el against him. Moreover, when the Kohen clarifies whether his wife sinned or not, he will appreicate the superiority of the Kohanim.