What is the significance of calling his father and mother?
Radak: This is an infant's first speech. This was at the same time as Achaz' son, "before he will know to detest evil and choose good" (7:15).
What is the meaning of "Yisa Es Cheil Damesek"?
Rashi: [Melech Ashur] will ascend to Damesek and seize it (Melachim II, 16:9).
Radak: The verse does not say who will carry the property of Damesek and the spoils of Shomron in front of Melech Ashur. This is like "va'Yaged l'Yakov", "va'Yomer l'Yosef" (Bereishis 48:2, 1) - the one who told them. There are many such verses.
Malbim: The verse depicts that the weak baby, who does not yet know to talk, will take the wealth, just like above, the infant will eat butter and honey (7:15) - a metaphor for consuming the entire nation.
What is "Shalal Shomron"?
Rashi: After Pekach was killed and Hoshe'a ben Elah became king, Melech Ashur came against him; Hoshe'a was a slave to him, and gave to him a gift and bribe (Melachim II, 17:3). All this was in Achaz' fourth year.