Why will the fig tree not sprout?
Rashi citing Targum Yonasan: Malchus Bavel will not last and will not rule over Yisrael.
Rashi: There is no success in any deed of Bavel from now.
Radak: This is a Mashal for the nations that will gather against Yerushalayim with Gog and Magog. They will not succeed. Rather, they will perish there. Those who escape and will not die, their limbs will be stricken - "v'Einav Timaknah v'Choreihen u'Leshono Timak b'Fihem" (Zecharyah 14:12) - they will be a sign for all nations that will go amidst them.
What is "Yevul"?
Radak: It is like fruits, e.g. "v'Nasnah ha'Aretz Yevulah" (Vayikra 26:4).
What is the significance of "Ein Yevul ba'Gefanim"?
Malbim: The rumors will say that when they see the entire world desolate and destroyed, they should look forward to salvation - the generation in which Ben David will come, great afflictions will arise, there will be many afflictions (Sanhedrin 97a). Vines will not give their fruits, there will be hunger, and many evils.
What are "Shedemos"?
Rashi: They are white (grain) fields.
Radak: They are seeded fields.
What is "Michlah"?
Rashi: It is an enclosure 1 for flocks. Radak - this is like "mi'Michle'os Tzon" (Tehilim 78:70), just there it has an Aleph, and here it has a Hei.
Malbim (Bi'ur ha'Milos): This is unlike Averos (or Urvos), from the root Arah. There, the animals are in the open air (Avir), not confined within walls.
What is the significance of "Gazar mi'Michlah Tzon"?
Malbim: When vegetation and animals are finished, this is a sign of Ge'ulah.
What are "Refasim"?
Radak: This is like Refes Bakar that Chazal discussed (cattle pens).