QUESTIONS ON RASHI
1)
Rashi writes: "'The great city' refers to Nineveh [based on Yonah 3:3]." Mizrachi asks - We find that the Midrash is unsure if the phrase "the great city" refers to Nineveh or to Resen. But perhaps it refers to Kalach, the last city mentioned?
1.
Gur Aryeh #1: Tosfos Yoma 10a answers that if it referred to Kalach, we would not need the word "Hi." That word implies that we are returning to a city mentioned earlier.
2.
Gur Aryeh #2: The subject of the verse is Resen, and the Midrash considers Nineveh as well only due to the verse in Yonah.