1)
What is the significance of "Yim'asem Elokai"?
1.
Rashi: This is not a curse, rather, informing that in the future, He will despise them.
2.
Radak: Elokai will despise them, for He is not their G-d, for "they did not heed Him."
3.
Malbim: Elokim will despise them themselves (not their children)
2)
Why will they wander among the nations?
1.
Radak: He will cast them away from His face.
2.
Malbim: He decreed this on them because He despised them.