1)
Did his enemies speak to him?
1.
Rashi: They said Alai (about me).
2.
Malbim: They spoke in front of me.
2)
Who are "Shomerei Nafshi"?
1.
Radak #1: Those who love me. They guarded my soul from the beginning, and now they join with my enemies to take counsel against me!
2.
Radak #2: They guard my soul for evil. This is like "Im Chatasi u'Shmartani" (Iyov 10:14) - to harm me every day.
3.
Radak #3: They guard my soul lest it be saved from them. This is like "Leshamro v'Lahamiso ba'Boker" (Shmuel I, 19:11).
4.
Malbim: Those who want to kill me.