1)
From where are they fleeing?
1.
Malbim: From the fortress.
2)
Why does it say "Ish Lefanav"?
1.
Rashi: Everyone will rush to flee from [the terror].
2.
Radak, Malbim: Everyone will be expelled from in front of it, to whichever direction he will flee. I.e. the fleers will not be gathered; a man will not console his colleague.
3)
What is the meaning of "la'Noded"?
1.
Rashi: This is [wandering,] like "Na v'Nad" (Bereishis 4:12).