What is "Chemah Apo"?
Radak #1: This is like Chemah b'Apo.
Radak #2: It is Samuch, as if it says Chemas Apo. We find like this - "k'Eifah Se'orim" (Rus 2:17), "Asefah Asir" (above, 24:22).
What is "Ezuz"?
Radak: This is the full form of Az (power), like "v'Ezuzo v'Nifle'osav" (Tehilim 78:4); usually, the second Zayin is omitted.
What will burn around?
Rashi: Other nations, in order that Yisrael be chastised - "Hichrati Goyim Nashamu Pinosam
Did he not know?!
Rashi: [Yisrael] knew, but was contemptuous, and was not concerned to understand and repent from his evil.
Radak: He did not know that this was due to his sins, and he should repent to make the evil depart.
Malbim: When the enemy destroyed cities on the borders of Yisrael, Yisrael thought that they are b'Shalom.
Why does it say "va'Tiv'ar Bo"?
Rashi: After the Nochrim around him were punished, the fire burned [Yisrael] himself.
Radak citing his father: This is when Sancheriv's army came to Yerushalayim.
Why does it say "v'Lo Yasim Al Lev"?
Malbim: Even after the fire (war) began to burn [Yisrael], he did not think to extinguish it and repent to Hashem.