1)
How does Hashem redeem them?
1.
Radak: Resha'im have evil intent for them, and Hashem saves them from them.
2)
Why does it say "Nefesh"?
1.
Radak: They want to kill them.
3)
Why does it say "Lo Yeshemu"?
1.
Rashi: They will not regret, and say 'we were wrong to trust in You.'
2.
Radak: The Resha'im will be guilty, and not those who trust in You.
3.
Malbim: Even though afflictions come on their body, there is no guilt in their Nefashos.