1)
What is the meaning of "Chamas Taninim Yeinam"?
1.
Rashi (citing Targum Onkelos): It means that the cup 1 of their feast of punishment is like the venom of serpents'.
3.
Seforno: It means 'those clusters 4 of wine
2)
What is the meaning of 'Rosh Pesanim Achzar"?
1.
Rashi and Ramban (in Pasuk 34): It means 'the head of a cruel python will come and punish them'.
2.
Targum Yonasan: It means that they are cruel like the head of vipers.