1)
Who are "Me'acharim Al ha'Yayin"?
1.
R. Yonah: They drink much wine.
2.
Malbim: After they tarried the entire night to drink wine, they come afresh to seek one who knows how to mix wine well, and they drink again.
2)
Who are "la'Ba'im Lachkor Mimesach"?
1.
Rashi: Mimesach is mixing wine. It is a noun, like Mimkar. These people investigate and check where they sell good wine.
2.
R. Yonah: They do not mix wine (dilute it with water) to blunt its strength, only to improve the taste. They investigate the amount of dilution to make a good taste.