How was her Zenus revealed?
Radak: It was known to all that she was Mezanah after other gods.
Malbim: Even though she separated from them, she persisted in Zenus, i.e. idolatry, until she did it in public.
What was Giluy of her Ervah?
Radak: Tzidkiyah disgraced the curse that Melech Bavel imposed on him, with a Shevu'ah in Hashem's name.
Malbim: She transgressed other Aveiros in public without shame - "va'Tefaseki Es Raglayich l'Chol Over" (16:25).
What is the meaning of "va'Teka Nafshi me'Aleha"?
Radak: I removed My Shechinah from her, that she will be Hefker to Melech Bavel, her enemies, and they will destroy the city and exile the nation, like He did to Shomron.
Malbim: I decreed Galus on her, just like on the 10 tribes.