Who says this?
Radak: So they will say in their confession when they leave Galus [that he did not despise their poverty in Egypt].
Malbim: The author says that his poverty did not come (a) because Hashem despises him, and does not supervise over him, like a person does not supervise over cats, or (b) because he hates him, for he is an abomination, or (c) because He does not supervise this lowly world.
What is the meaning of "v'Lo Shiketz"?
Radak: He did not consider an abomination. This is like "Al Teshaktzu Es Nafshoseichem" (Vayikra 11:43).
What is "Enos Oni"?
Rashi #1: The cry of the poor. Every "Aniyah" in Tanach is screaming.
Rashi #2: Enos is humility - "Le'anos mi'Panai" (Shemos 10:3). He is humble and prays to You.
Radak: Enos is a noun; it is connected to Oni (poverty).
What is the tense of "Shame'a"?
Radak: It is past tense, like "Ki Chafetz b'Vas Yakov" (Bereishis 34:19).
Malbim: (It is present.) When he screams, He hears.