Why does it say "me'Ein Kamocha"?
Radak: From what we see and know that there is none like You in higher or lower beings, we know that You are great, and Your name is great in Gevurah.
Malbim: You include all perfections. There is no Sheleimus like You.
Why does it say "Gadol Atah"?
Malbim: (a) Ha'Gadol is relative; it is bigger than something smaller, and it is feasible that something is bigger than it. You are Gadol Yourself, without comparison. (b) You are the first cause, and [cause] the end of all results.
Why does it discuss Hashem and His name?
Radak: This teaches that He is His name, and His name is Him.
Malbim: One can be intrinsically Gadol, but does not act outside himself. E.g. a great Chacham who understands everything, but cannot create them. One's name can be great but he is not intrinsically great, e.g. a great Gibor famous for his strength and ability, but he is not intrinsically great, for he does not understand things as they are. You are intrinsically Gadol and the source of all Chachmah, and Your name is great via Gevurah and ability 1 .
Malbim: Some pictured Hashem as a Chacham who arranged everything with His Chachmah, but thought that He lacks ability to carry them out, therefore He has helpers to conduct matters according to His Chachmah; the Gevurah is theirs. Some said oppositely, that Gevurah is His but not Chachmah; He needs advisors. The signs of Shamayim show the counsels and decrees from His advisors. Due to both [errant] understandings, people feared signs of Shamayim and served other gods, because they thought that they have power to conduct matters, or they counsel how to conduct matters. The verse teaches that You are Your name are Gadol - the Chachmah and conduct is all Yours; You have no helpers.