What is "Zedon Libecha"?
Targum Yonasan: The evil of your heart.
Malbim: It is intentionally denying principles of Emunah to speak deceit and derogatory matters about Hashem.
What was Edom enticed to do?
Rashi (Yirmeyah 49:16): To harm [Yisrael].
Radak: (a) To speak harshly. (b) To increase anger against your brother Yakov.
Malbim: To ascend to dwell at the height of the world.
What is "Shochni"?
Radak: It is Shochen; the Yud is extra. Radak - the same applies to "Chotzvi Marom Kivro" (Yeshayah 22:16), "ha'Yoshvi va'Shamayim" (Tehilim 123:1) and similar verses.
What are "Chagvei ha'Sela"?
Rashi: [Places of] fear 1 . This is like "v'Haysah Admas Yehudah l'Egypt l'Chaga" (Yeshayah 19:17). The Vov is extra, like the Vov in "Katzvei" (Tehilim 65:6) and "ki'Mtachavei" (Bereishis 21:16). The root [of ki'Mtachavei] is only the letters Tes and Ches.
Rashi (Shir ha'Shirim 2:14): They are clefts or breaks in the rocks. This is like "Yachogu v'Yanu'u ka'Shikor" (Tehilim 107:27), "v'Haysah Admas Yehudah l'Egypt l'Chaga" (Yeshayah 19:17).
Radak: Chagvei is like "Chug ha'Aretz" (Yeshayah 40:22, the ball of the earth), i.e. around the rock. This refers to the top of the rock on which the tower is built. This refers to Har Se'ir.
Radak citing Targum Yonasan: Mountain peaks.
Why does it say "Shochni b'Chagvei ha'Sela"?
Rashi: Edom relies on the staff of his ancestors Avraham and Yitzchak, but they will not help him.
Why does it say "Mi Yorideni Aretz"?
Radak: [When you dwelled in Har Se'ir, you thought that you are protected in it,] and no one will make you descend from it.
Malbim: You thought that your Emunah will spread greatly, and via this Malchus Edom will be elevated at the end of days, to the point that you need not fear any person.
What is "Merom Shivto"?
Radak: It dwelled in Chagvei ha'Sela, i.e. Har Se'ir.