1)
Whom do they seek to distance from the Mikdash?
1.
Rashi: Me. Radak 1 - they sin in front of Me to distance Me.
2.
Malbim: The power that does evil. This is the purpose of their Avodah. Really, this distances Hashem!
1
Radak: There should be a Sheva under the Ches in Lerachakah, like "v'Chano Nechoshes Lerachtzah" (Shemos 30:18). There is Kamatz Chataf to beautify the pronunciation.
2)
What other abominations do they do?
1.
Malbim: They are acts intended to bring down influence of good from the Ma'arachah.