Why does it say "Ka'asher Shamemu"?
Rashi: Many nations are astounded 1 at them, when they see their lowliness. They will say, how deformed is his appearance from being human! Their form is darker than others, like our eyes see. Radak citing Ibn Ezra - many Nochrim think that a Jew has a different form. They ask if he has a mouth or eye. So it is in Eretz Yishmael and Eretz Edom.
Radak (53:12, citing Targum Yonasan): Like Beis Yisrael thought
Radak: This is like "Mashmim b'Socham" (Yechezkel 3:15).
What is the grammatical form of "Mishchas"?
Radak: It is an adjective. There is a Chirik under the Mem; this is like "ha'Mivdalos" (Yehoshua 16:9).
Why does it switch from second person ("Alecha") to third person (Mar'ehu v'So'aro")?
Radak: Verses often do so.