What ropes did He put on him?
Rashi: My command is severe on you as if you were bound in ropes, that you cannot turn from side to side.
Malbim: This is like it says above (3:25) "Nasenu Alecha Avosim", that you cannot leave your house.
What are "Yemei Metzurecha"?
Rashi: The number of days that I decreed on you. Radak - they were 430, corresponding to the years of their evil. In those years, they nullified 70 Shemitah years 1 .
Radak counts 70 Shemitos in 350 years, and also seven Yovelos. This is like R. Yehudah, who says (Rosh Hashanah 9a) that the 50th year (Yovel) also counts as the first year of the next Yovel cycle. (PF)
Why does it say "Metzurecha" (plural)?
Radak: One is for Shomron, and one is for Yerushalayim.