1)
Does Hashem literally speak to them?
1.
Radak #1: His anger that He sends against them are His words.
2.
Radak #2: Yedaber is [an expression of a plague,] like "Dever Kaved Me'od" (Shemos 9:3), and "va'Tdaber Es Kol Zera ha'Meluchah" (Divrei ha'Yamim II, 22:10).
2)
What is the meaning of "Eleimo"?
1.
Rashi: This is like 'Aleihem'.
2.
Radak: This is like "Eilei ha'Aretz" (Melachim II, 24:15), i.e. strong people of the land. The other Perush (Aleihem) is better.
3)
Before, Hashem laughed. Why does He now speak amidst anger?
1.
Radak: This is after He hears their words and pride.