What is the meaning of "Gam me'Es Zeh Tetz'i"?
Radak: From here you will leave (be exiled); those that you rely on will not help you.
Malbim: You will regret going [to Egypt for help].
Why does it say "v'Yadayich Al Roshech"?
Radak: This is the way of a woman who screams about her downfall. She goes with her hands on her head. E.g. Tamar "va'Tasem Yadah Al Roshah va'Telech Haloch v'Za'akah" (Shmuel II, 13:19).
Radak citing Targum Yonasan: The shame of your sins is on your head.
What is the meaning of "Ma'as Hashem b'Mivtachayich"?
Radak (3:1): Hashem despises you due to the ones in whom you trust.
Malbim: Hashem despises the means in which you put your trust.
What is the meaning of "v'Lo Tatzlichi Lahem"?
Radak: You will not succeed due to them.
Malbim: You will get the success you seek from them because they are against Hashem's will.