Why did He say "v'Atah"?
Malbim: Now that you caused your fall
Why did He say "Mah Lach l'Derech Mitzrayim"?
Rashi: Why do you abandon Me and trust in Egypt?
Radak, Malbim: Why do you go to seek help from Egypt [and Ashur] - your help is in your place!
Radak: Why do you [want to] attach yourselves to Pharaoh, Melech Mitzrayim?
Why did He say "Lishtos Mei Shichor"?
Rashi: They drowned your male [babies] in the Nile river. Shichor is the Nile - "Min ha'Shichor Asher Al Pnei Mitzrayim" (Yehoshua 13:3).
Radak: If you would go in the straight path, you would not need to toil to [go to] far places. It is as if you desire to drink the water of Shichor (Malbim - in place of the source of flowing water that you abandoned), or the water of the river of Melech Ashur!
What is the meaning of "u'Mah Lach l'Derech Ashur"?
Rashi: Why rebel against Me, so you will be exiled to Ashur, on the other side of the Peras river?