How will he be clothed with a curse?
Rashi: [Esav] entered himself into a curse. He is pleased with casting off the yoke of Korban and Birkas Kohanim 1 , and the curse of the nations. Radak - it will be k'Mido (like his measure); he will be wrapped in it.
Malbim: The curse that he measured (made appropriate) for David, it should be fit to his measure.
He despised the Bechorah, i.e. selection to serve in the Mikdash. (PF)
What do we learn from "va'Tavo cha'Mayim b'Kirbo vecha'Shemen b'Atzmosav"?
Shabbos 86a: This hints that anointing is [forbidden] like drinking on Yom Kipur 1 .
Radak: The curse should enter him like water that a person drinks, and like oil that one anoints for aching bones; it is absorbed into the bones. Malbim - he will be cursed externally and internally.
Tosfos (Nidah 32a): This is an Asmachta; the Isur is mid'Rabanan. They decreed only about oil, but not about pig's lard or Chelev. Beis Yosef (YD 81:2) - this is because oil is absorbed more in the body.