What is the meaning of "Ad Es Bo Devaro"?
Rashi: Until the time for Hashem to fulfill His decree that Yisrael descend to Egypt.
Radak, from Shocher Tov #1: It is until [Yosef's] word came in front of Pharaoh - Sar ha'Mashkim mentioned him to Pharaoh.
Radak, from Shocher Tov #2: Until Hashem's word came. When Yosef told Sar ha'Mashkim "Ki Im Zechartani Itecha Ka'asher Yitav Lach" (Bereishis 40:14), Hashem said, you will have two more years of afflictions.
Malbim: (a) Until will come the matter mentioned above "Davar Tzivah l'Elef Dor" (verse 8) - was aroused Hashem's word about Bnei Yakov, not to touch them. Also refer to 105:19:2:3.
How did "Imras Hashem Tzerafas'hu"?
Rashi: Hashem tested him. He overcame his Yetzer for his master's wife, and due to this he was afflicted and incarcerated.
Radak: Hashem arranged that Pharaoh dream, and only Yosef could interpret it, and he was like refined silver in front of Pharaoh, and Sar ha'Mashkim said "like he interpreted for us, so it was" (Bereishis 41:13).
Malbim: Came the time that the refining in the iron smelting pot [was finished], so he will stand and be tested in his virtue.
