We learned in Kesubos 65 the impact of different amounts of wine on women concluding that 4 cups will have a very severe impact on them.
I don't remember seeing this play into the seder requirements for 4 cups.
Why not? For example, maybe we should insist they only drink grape juice?
Especially since the Seder night is one of the ones that Al Pi Kabalah is not proper for Tashmish? So how does this jive?
The Ben Yehoyada answers that since there are breaks between the different cups of wine of Pesach, they do not have such a negative effect.