Why does the Pasuk add the word "Kol"?
Rashi: To include where the victim is a Katan or a woman. 1
To which of the four types of death is the murderer sentenced?
Targum Yonasan: He is sentenced to Hereg (death by the sword). 1
Even though Misah Stam generally implies death by Chenek (strangulation).
Why is the connection between the final Pesukim and that of the Megadef?
Seforno: After conveying the difference between cursing Hashem and cursing a judge or a king, 1 the Torah illustrates how the same callous act can result in different punishments, depending on the status of the victim. And it gives three examples, one regarding the act of killing, 2 one regarding the act of wounding, 3 and one regarding the act of wounding a person. 4
Seforno: For killing a person one is Chayav Misah, whereas for killing an animal, one pays.
Seforno: For wounding a person, one ought to be punished bodily, but because such an assessment is impossible, the striker is heavily punished monetarily, and pays five things (refer to Shemos 21:18:1:1 and the note there), whereas for wounding an animal one has to pay only for the damage.
Seforno: For wounding another person one pays money, whilst someone who wounds his parents is sentenced to death.
Why do we need this verse? It already says (Shemos 21:12) "Makeh Ish va'Mes Mos Yumas"!
Refer to Shemos 21:12:2:1.